Urine microscopy and culture remains one of the most commonly requested tests in the Microbiology laboratory. This presentation reports on the introduction of the APAS® Independence (Clever Culture Systems, Switzerland) to automate urine culture plate imaging and interpretation as a means of streamlining laboratory workflows and reducing time to results.

The APAS® Independence is a stand-alone in-vitro diagnostic instrument that utilises AI machine learning, via a software analysis module, to sort urine culture plates into four designation categories (“Probable”, “Review”, “Doubtful”, “No Growth”) based on the likely significance of the culture. It uses colony enumeration as the primary decision-making driver.  The “Probable” and “Review” categories require intervention by a scientist to further evaluate cultures and to perform identification and susceptibility testing as required. The “Doubtful/No significant growth” and “No Growth” categories represent samples that can be automatically reported through instrument interfacing, providing they meet pre-determined criteria.

Following extensive evaluation and verification, the APAS® Independence was introduced into the routine urine workflow in July 2024. Its introduction highlighted the need for adaptability, and for a culture of psychological safety when embarking on any change process involving automation. It continues to offer efficiencies in workflows, diverting scientist time from reading negative cultures to more complex laboratory tests, and in reducing the time to reporting urinary antimicrobial susceptibilities.

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‍Presented at: The Australian Society for Microbiology Clinicon Conference, Adelaide Convention & Exhibition Centre

Author/Presenter: Lisa Brenton, Microbiology, St Vincent's Hospital Melbourne, Fitzroy, Vic, Australia

Date: July 15, 2025

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